Increased expression of granzymes A and B in fatal asthma
نویسندگان
چکیده
منابع مشابه
Increased expression of granzymes A and B in fatal asthma.
The granules of effector cytotoxic CD8 cells and natural killer (NK) cells contain a family of serine proteases called granzymes (granule-secreted enzymes) [5]. Granzymes are stored in the cytotoxic granules and require perforin to be delivered into the target cells to exert their cytotoxic function [5, 6]. Granzymes can also be released to the extracellular space and cleave extracellular matri...
متن کاملIncreased expression of granzymes A and B in fatal asthma
The granules of effector cytotoxic CD8 cells and natural killer (NK) cells contain a family of serine proteases called granzymes (granule-secreted enzymes) [5]. Granzymes are stored in the cytotoxic granules and require perforin to be delivered into the target cells to exert their cytotoxic function [5, 6]. Granzymes can also be released to the extracellular space and cleave extracellular matri...
متن کاملthe investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
Prevalence of Near Fatal Asthma and Related Risk Factors in Asthmatic Patients in Kerman
Background & Aims: Asthma is one of the most common diseases worldwilde that can be prevented with optimal access to medical care. Since there is no data about the prevalence of risk factors of death caused by asthma in our region, the present study was performed to determine the prevalence risk factors of fatal asthma in asthmatic patients. Methods: This study was done on 200 asthmatic patient...
متن کاملExpression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma.
BACKGROUND The mechanisms leading to death from asthma are not completely understood. Recent studies suggest the involvement of the anaphylatoxins C3a and C5a, generated during complement activation, and their receptors C3aR and C5aR in the pathogenesis of asthma. OBJECTIVE The aim of our study was to investigate the expression of C3aR and C5aR in fatal asthma. METHODS We analyzed lung tiss...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2015
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00213814